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Lovenox and fatigue?
Started by zara
Posted: January 11, 2007 at 23:53
I am wondering if others have found fatigue to be a side effect of Lovenox injections? This is my third time doing the Lovenox injections but the other times I stopped at 10 doses/shots. This time I am on about my 14th shot of a 20-shot course and I am SO TIRED. It's not like a sleepy, not enough rest tired, I just want to lie down all the time, almost like having a mild case of the flu. I was wondering if others have experienced this.
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Re: Lovenox and fatigue?
Reply #1 by Carrie
Posted: April 13, 2007 at 01:06
Hi,

Yes I have experienced this too. Whilst on the injections I was in a world of my own. I always wanted to lie down (although couldn't wait to get out of the hospital) and felt as really 'foggy'.

I am not on the injections anymore and am just on Warfarin but still have the same feelings. It isn't as bad but I am constantly tired and can't concentrate.

I mentioned this to the Anticoagulant nurse and she said that a lot of her patients had said they felt this way.

I also found this
http://www.topix.net/forum/drug/coumadin/TK8TSJ8UJAHO1JENH/p5

Hope this helps.


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Re: Lovenox and fatigue?
Reply #2 by Joy
Posted: May 31, 2007 at 15:32
I feel like I can not get enough sleep and I can't concentrate on my work. I keep forgetting what I'm doing! I constantly feel like I am on the edge of coming down with something. I hate it!
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Re: Lovenox and fatigue?
Reply #3 by Robert
Posted: May 16, 2008 at 18:38
I am a 38 year old who developed DVT(March,08) in the back of right knee and eventualy PE.This happened during a ice hockey match. I was on Lovenox in hospital and then Dr. gave me Coumading which made me very sick to my stomach.My side eefects were so bad I requested another medicine so I am back on Lovenox,100mg twice daily..the shots hurt but still better than coumadin.I like the rest of you fell very tired and if I could i would sleep all day. I am having ultrasound in June and hopefully the clot is gone,so i can stop taking this medicine anf get my life back.
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Re: Lovenox and fatigue?
Reply #4 by John in Dallas
Posted: May 16, 2008 at 19:44
After being diagnosed with dvt, I was placed on lovonox because of an unusually high INR at the onset. This stuff caused continual tiredness and being in a fog. My skin had a prickly or crawly sensation at times in certain spots. I noticed symptoms worsened about 4 to 5 hrs after my injection. I also had anxiety and aggitation at times. My hematologist put me Arixtra after I complained to him about the side effects. After a few days on Arixtra, my symptoms diappeared and I felt totally normal again.

After a few weeks on Arixtra my hematologist put me on coumadin since the high INR was no longer an issue. The coumadin was way worse than Lovonox. I was in a total mental fog all the time, had anxiety and aggitation, increased resting pulse rate, tingling in hands and feet, prickly sensations, and could not concentrate at all. I was on the coumadin for a month.

The hematologist put me back on Arixtra and again all symptoms disappeared after about six days. The only symptom I have is a very slight tingling in my hands which I had from day one on anticoagulants but was a lot worse on Lovonox and Coumadin. I'm happy taking the Arixtra and don't mind the injections. Also, I don't have to have my INR checked all the time. The downside is it's expensive and some insurances won't cover it.

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Re: Lovenox and fatigue?
Reply #5 by Janine Renee'
Posted: May 17, 2008 at 02:22
I never had any probs with Coumadin while on it since 2000.
I have been on Arixtra now for 2 weeks now, I will be on it for life. Yessss the cost...Wow.. $4,400 a month.
THANK GOD I was able to get help with it. I feel blessed for that!! I FREAKED when I was told I would have to be on it forever, but that is just how it has to be. No choice, I had another clot develop with an INR of 4.5
If it helps to NEVER get another clot it sure is worth it!!
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Re: Lovenox and fatigue?
Reply #6 by Roger
Posted: July 17, 2008 at 21:54
Coumdin-Lovenox-back to warferin and now on Arixtra. Been through them all but when you get a clot at 3.7 all my docs agreed its time for a change. Been on Aristra now about 2 months and I too don't mind the injections and i love the fact that I don't have to have my life on hold for those continous blood tests BUT I now find myself alot more tired than when I was on other blood thinners.

First they tell me I would be on it for life [$2,000/month] now after three months they want me to go back to warferin.

Give me some time and I will report back if after returning to just too tired.
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Re: Lovenox and fatigue?
Reply #7 by Sharon
Posted: July 18, 2008 at 06:32
I've taken them all as well. Clotted thru all but Arixtra. I can't say that it would keep me from clotting in a hypercoagulable state, bcs I came out of that before I started taking it. I have been very tired ever since I got home from the hospital (got home many times, went back many times) and don't know if it has been particularly better or worse with any of the anticoagulants.

There are a couple of other possibilities to explain the fatigue that we all struggle with--

1) Adrenal insufficiency. This is caused from prolonged physical, psychological or emotional stress. Numerous physical or emotional traumas can also wear out your adrenals. http://www.stopthethyroidmadness.com/adrenal-info/ I was diagnosed with this after the multiple recurrent clotting last summer.

2) Grief or depression. We have all had major life changes and losses to grieve--out health if nothing else, but many of us have also lost the ability to have children, loved activities and abilities, dear pets (horses), some on this forum are surviving spouses of persons who died from DVT. Grief and loss even if dealt with in healthy ways can have periods of depression. If we don't deal with it in healthy ways, we may prolong and intensify the depressive symptoms which are fatigue, lethargy, loss of interest in normal activities or people, sleep distrubances--insomnia or sleeping too much, appetite changes (can go either way from the norm), and feelings or sadness, being overwhelmed, out of control, helpless and/or hopeless.

I think to some extent, that it is hard to sort all of these possibilities out from one another--since we start the anticoagulants at the time we are shocked with the news of DVT and all it means to our lives. We begin our grieving processes then as well whether we are aware of it or not.

Hope I haven't depressed anyone. The good news is that this forum where we share support and information is one of the best antidotes for depression and moving thru grief in a healthy way.
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Re: Lovenox and fatigue?
Reply #8 by Donnjo
Posted: January 9, 2009 at 16:48
Diagnosed with DVT on December3, 2008. Given Lovenox and sent home from emergency. December 4 was started on a daily dose of Lovenox and must continue until February 4, 2009. I am allergic to Warfarin and have a history of heart problems, diabetes and poor circulation; which is the reason for such a long time on Lovenox. I find I am very tired all the time and like to sleep a lot; I also have severe bruising and hematomas in the injection sites. Thank you all for sharing your stories - I don't feel so alone now.8
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Re: Lovenox and fatigue?
Reply #9 by Barbara
Posted: January 9, 2009 at 18:56
Today, I received the news that my second blood clot is gone. It's been a long haul for me. I was sent home with the blood clot on September 5, 2008 with Lovenox in the stomach for 30 days and Coumdin. I am still on Coumdin. I have reported to my doctor and nurse that I am TIRED..so very TIRED. At the end of the day, I can barely make it. I try taking the Coumdin at night to see if that helps but it doesn't. Does anyone have an explanation?
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Re: Lovenox and fatigue?
Reply #10 by rickylaroy
Posted: May 7, 2010 at 04:57
Just locate this site and was so glad, i thought that i was the only one feeling like a sleepy space creature with ADD.... i have only three more months on this stuff , hope that i can last
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Re: Lovenox and fatigue?
Reply #11 by Amy
Posted: August 24, 2010 at 16:04
Just started Lovenox 4 days ago, 22 weeks pregnant. After the first day, I felt like I was
coming down with the flu and felt almost narcoleptic at times during the day. I would
find myself just staring through people and then I would nod off for a second! Not a
good combo when you have a two year old full of energy! So glad I found this site, BUT
why aren't fatigue and dizziness listed as side effects by the manufacturer??!?!?!?!?!?
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Re: Lovenox and fatigue?
Reply #12 by Jen
Posted: November 18, 2010 at 05:48
No wonder why!! I thought I was just being lazy.... I have an essay due tomorrow but I cant seem to find the strength to write it or the focus. I dont know what to do!! I want to cry because I am unable to write it and feel stupid because of it.
Amy, I would love to know why its not listed as side effects either!??!?!
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Re: Lovenox and fatigue?
Reply #13 by JERRY
Posted: January 5, 2011 at 23:29
I have had multiple DVT's, PE's, clots in my leg, head, and now arm. The last 2 I had while on coumadin therapy. I currently just got switched to lovenox while in the hospital with my current clot in my entire arm. I have been not able to stay awake if I sit down for any length of time and I have my first appt. with my hemotologist coming up in a couple of weeks. Hopefully they can find out why. I have spent 20 years in the service and have been retired for almost 6 years and it is hard to accept being this tired. I feel for all of you, it is not an easy road, but as with some of you mine is lifelong treatment.
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Re: Lovenox and fatigue?
Reply #14 by Misssassy
Posted: November 20, 2011 at 18:35
I have been taking daily injection for one week ...... I also have been on
chemotherapy for quite awhile.....I think this fatigue is worse by far.......as
someone posted it feels like the beginning of flu symptoms ........ Has anyone
found a difference between pill or injectable..also any hait loss ...thanks for the
time ..embrace the day 401mi1
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Re: Lovenox and fatigue?
Reply #15 by Michelle
Posted: November 20, 2011 at 20:24
I was getting Lovenox injections twice a day for a month and a half. No problems with fatique or feeling tired. I'm on warfarin only now and still don't have a problem with that. I take 10-mg a day and my INR is usually just under 2, 1.7 at my last check, I'm not great at being regulated. I'm actually quite thin (but very tall) and most women my size don't need quite so much (I was told by the pharmacist anyhow) but I live an extremely active life and I guess I metabolize it quickly. I've been on it for 4 months now and about 2 weeks ago started noticing hair loss. I've always been a "shedder," but now it seems worse. I have hair about half way down my back though, so maybe it's really noticable because my hair is so long. Anyhow, I know they both suck, but these meds saved my life so thank God for them. Once my blood clot is gone I get to go off of them since my DVT was caused following a tummy tuck surgery. I have roughly 3-5 more months on them I'm told, or whenever an ultrasound comes back oky-doky.
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Re: Lovenox and fatigue?
Reply #16 by Ben
Posted: April 5, 2012 at 21:17
I am now on Lovenox again. First time was just a bridge to Coumdin after having a rib resection for Thoracic Outlet Syndrome and clotting in the Subclavian Vein.

I experienced tiredness on Coumadin, asked my doctor and he said it was from having a blood clot.

I had a second clot, angeos for that, now clot free, and now am on Lovenox and am feeling all the things described above. I feel like I'm going to fall asleep at any moment, sometimes while driving, checked out for a second at a stop light. Often feel like I just need to lie down suddenly.

Will need to discuss with Hematologist.

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Re: Lovenox and fatigue?
Reply #17 by Lisa 2012
Posted: April 6, 2012 at 03:40
Sharon,

You and I could be twins. I feel the same way. It's like no one understands how I
feel and what I'm going through. Up until now I fro all alone. I mean it's like one
day I was feeling motivated about my new look ( lost 62 pounds) feeling good
about myself! Working contract at my dream job moving towards a permanent
position with the company, working on my Masters degree, busy wife and mother,
etc I mean I was the super woman! I'm 42 and look 35 lol
Then in one second I had yo slip and fall develop a DVT and here I am. Sharon
you said everything I've been feeling for the last three weeks!
I find myself crying because I want yo workout or enjoy a nice evening with my
husband and cant.

I'm like Sharon, sure hope I hadn't depressed anyone
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Re: Lovenox and fatigue?
Reply #18 by Lyn
Posted: July 16, 2012 at 21:00
My husband began a 4 day course of Lovenox after having pins removed from a repaired fracture that he suffered one year ago. He is very lethargic especially in the afternoons and evenings and a bit confused all day. I believe that this is a real side effect to the drug. He had more energy and clearer thinking last year after major surgery and no Lovenox than this year with the minor surgery and doses of Lovenox

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Re: Lovenox and fatigue?
Reply #19 by Susan
Posted: August 18, 2012 at 11:41
I have been on Lovenox for about 5 weeks, and hope to stop it in about a month. I notice some tiredness, but I just had a hysterectomy, so not sure what is making me tired.
I felt the way Sharon does when I was on Xarelto: absolutely dreadful! I would rather be a bit sleepy and have to give myself shots than feel like a zombie.
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