DVT deep vein thrombosis forum

       Home    1 2 3 4 5 6 7 8 [Next Page>>]

number of replies (159) - Page 1 of 8
Nattokinase
Started by Lisa
Posted: August 23, 2007 at 20:38
Is anyone taking Nattokinase or know of any side effects of taking it. I just want to hear straight from a person whose taking Nattokinase what it's like. I found this site
http://www.thehealthierlife.co.uk/article/3574/deepveinthrombosis.html

about it and I can't seem to find anything bad about it. I just want to know anyone whose currently taking it, what you think about it and what kind of side effects you have had from it?
2190
Re: Nattokinase
Reply #1 by Richard
Posted: August 28, 2007 at 23:32
I'd never heard of this until I read your post, and, yes, from my limited reading on the Internet, it does seem to be a worthwhile product.

However it concerns me that if it really is that good, why is it not recommended by doctors and consultants? You'd think that if it was effective, they'd be recommending to people (like me) who have just finished a course of warfarin to help prevent a second occurrence.

So unless anyone can provide some serious findings on Nattokinase, I think I'm going to give it a miss for the time being.
2223
Re: Nattokinase
Reply #2 by Tammie
Posted: September 23, 2007 at 22:13
My husband was diagnosed with two clots in his right popiteal vein over labor day weekend. We went to ER. It was diagnosed through ultrasound and he was put on Fragmin. He finished the Fragmin and went on Coumadin. When we returned to our regular doctor, he discontinued the Coumadin and put him on Nattokinase. He said it would thin the blood as Coumadin does and break down the clots slowly.

Husband is doing pretty well. He is wearing compression stocking on his right leg. His leg still swells mildly after a day of being around the house and up and down from his chair working on computers. It goes down at night though after sleeping. No redness, but he is experiencing some leg pain. He says it is soreness, but in no way debilitating.

Tammie
2374
Re: Nattokinase
Reply #3 by Shana
Posted: November 4, 2007 at 01:48
Tammie - where are you in the country? I am in California, and plan on asking about Nattokinase for myself when I come off Coumadin.

Thanks!
2581
Re: Nattokinase
Reply #4 by Sharon
Posted: November 7, 2007 at 05:49
I'm taking it w/ good results. See my posts on natural suppliments or anticoaguant or something like that. Dr's don't prescribe it bcs it isn't tested by FDA and they don't want to take the risk of not having standards--which makes sense until all their meds fail for some people.
2630
Re: Nattokinase
Reply #5 by Matt
Posted: January 20, 2008 at 11:45
Also...in answer to Richard's question. Since Nattokinase is derived from a food source, and can't be patented the drug companies won't do major reasearch on it (no money in it) and doctors won't look into it unless they have a keen interest in holistic cures - most don't.

Natto seems to be even better than Coumadin in that it has a significant lytic action as well (it dissolves clots) whereas Coumadin simply thins the blood (which Natto does as well).

I would love to hear if any other people use this. I'm considering using it long term after I'm done with Coumadin.

Matt
3697
Re: Nattokinase
Reply #6 by Maria
Posted: January 20, 2008 at 17:36
I've been considering it as well and have been looking for more in-depth research. It seems there is no other substance that actually disosolves clots. Just this week I saw a doctor of natural medicine (with a 40 year practice) who highly recommended it for me. Based on his recommendation, and from what I've read, I will definitely take it when I'm off Coumadin.

Though I am ony a month into treatment, I am thinking about taking it along with, or instead of Coumadin Even though I hate the side effects of Coumadin, I am still a little cautious about taking any medication or supplement changes without getting more thorough research.

My GP and Hematologist didn't know about it. I read that if you do take it while on Coumadin you should get your levels tested more frequently the first week. I bet we might find some Japanese studies!

Please let me know if you find any other information. Thanks!
3704
Re: Nattokinase
Reply #7 by Sharon
Posted: January 21, 2008 at 06:36
I have some links to a few studies and will try to send them when I am on my home computer where I saved them. It also lowers blood pressure. I have taken it for some time and hae no negative side effects. I take it w/ my shot (Arixtra) since I refused to take coumadin bcs I was hypercoagulative for so very long and could not ever get therapeutic on the stuff--coumadin that is.

My doc has been willing to do the D-dimers routinely (I had the first negative D-dimer after 30 days of clotting once I started the NK--nattokinase) and he has also run the 'fibrin split products' which measures the lysing effect it is having. FSP has always been higher than normal--meaning I am dissolving clot. (It's a blood test that measures the by-products of dissolved thrombus in the blood)My hematologist is quick to point out that it is not as high as when they use Tpa to dissolve clot--but I am quick to point out that you don't want to walk around that anticoagulated! He was surprised to see that it had any effect at all--he thought I was "wasting my money" at first. I am just glad to be taking something that we can show is having an effect on dissolving the clot. I have cleared 1 1/2 of the 3 veins that were clotted in the right leg. I have very litle swelling.

You can read abstracts of articles on Pubmed--this impressed my doc that there were articles published by doctors--he didn't want to hear about it until then.

You do want to check your anticoagulation if you get on it. They were able to reduce my dosage quite a bit once I started the NK. Good luck.
3720
Re: Nattokinase
Reply #8 by Maria
Posted: January 21, 2008 at 10:45
Great information Sharon...Thank you! I will look these up so I can go "armed" to my next doctor's appointment!

Maria
3724
Re: Nattokinase
Reply #9 by Matt
Posted: January 21, 2008 at 12:51
Sharon:

Nice work! Do you have any particular PubMed articles you would reccomend? Maybe you can link a few in so people that read this thread will have some initial ammunition.

I hope this leads to a little more awareness of this promising substance!

Matt
3728
Re: Nattokinase
Reply #10 by Matt
Posted: January 21, 2008 at 12:52
Oh yeah...Sharon...what natto supplement do you take, how much, etc.?

Thanks!
Matt
3729
Re: Nattokinase
Reply #11 by dero www.lifeafterdvt.forumotion.com
Posted: January 21, 2008 at 22:59
Here is a site that has an interesting read on "Nattokinase"
http://www.raysahelian.com/nattokinase.html
3741
Re: Nattokinase
Reply #12 by Maria
Posted: January 21, 2008 at 23:53
Hi Matt,

I've found an abundance of information on Nattokinase by searching on www.alltheweb.com. Google did not list many of the sites this search engine referenced.

Some of the brands still include some Vit K in their formulation. (Sharon mentioned some suppliers that DO NOT include it). That's one reason some of the articles caution taking it if you are on Coumadin. From what I've read however, it appears to be safe to use both, but you should have the specific blood tests they mention.

Still have lots of links to check out...

3744
Re: Nattokinase
Reply #13 by Richard
Posted: January 22, 2008
Thanks Sharon for that useful information.

I started taking Nattokinase a couple of weeks ago (hopefull to help with an air flight next week, and was wondering how you can prove that it is doing some good; I was thinking you can only prove it DOESN'T work when you get another DVT! But it appears that your tests give an indication that it IS doing some good for you at least.

Are you getting your blood tests done under your health insurance? Here in the UK, while I had excellent treatment under the NHS, I think they'd be very reluctant to do any follow-up tests or scans just to see how my veins are recovering. (I'm now 15 months on from my DVT).
3745
Re: Nattokinase
Reply #14 by Donna
Posted: January 22, 2008 at 18:29
Hi Richard, I too am in the UK and went private when I came off warfarin as I was a bit worried as to whether my clot had gone.Was told I didnt need any further tests as six months on warfarin would have dissolved it but was advised to have clexin injections before any longhaul flights and my GP would arrange these.
3757
Re: Nattokinase
Reply #15 by dero www.lifeafterdvt.forumotion.com
Posted: January 23, 2008 at 05:22
Just a clarification, warfarin does not dissolve the clots, it's not a clotbuster and even thought it's commonly known as a blood thinner, it does not thinn the blood. Warfarin is an anticoagulant therefore it cuts down on the coagulation of the blood.
3764
Re: Nattokinase
Reply #16 by Sharon
Posted: January 23, 2008 at 06:45
Hey Everyone--

Sorry I have not been able to get the links for you yet. My Dad and my nephew have both been in the hospital for more than a week.

Matt--I did not save the links for all the PubMed articles, bcs if you are not a doctor, only the abstracts are available. However, you can do your doctor's homework and read all the abstracts and make him or her a list of the best links on NK. I simply printed the ones I wanted him to take a look at, and he had his fellows look them up and report to him.

I have links to other articles and a list of suppliers that sell the best form of nattokinase. There are apparently many imitation brands. I use the brand made by Allergy Research Group, although the brand made by N-ZimeCeuticals and Dr. Holsworth is also one of the best. He is the doc that developed the original for the Allergy Research Group and then started his own company later. He will email answers to questions on one consult and afterwards, only if you purchase from his company.

http://www.allergyresearchgroup.com/Nattokinase-NSK-SD-100-mg-180-Softgels-p-268.html

http://www.nzymeceuticals.com/

I take 400 mg/8,000 Fibrinogen Units (2 softgel tablets in the morning and 2 in the evening). I take additional doses if I have any injury to my legs. I had to come off the anticoagulant for a biopsy of my thyroid tumors and took extra NK to keep from becoming hypercoagulant again (6-8 per day). Didn't clot, so I guess it worked. I know of people who have taken up to 20 per day when they got a PE.

One study documents an attempt to overdose rats w/ 700 times the recommended daily human dosage and there were no ill effects (except 1 of the female rats got diarhea, but since none of the oters did, she may have just been having a stressful day otherwise!). I say they had no ill effects--until autopsy that is, but none from the NK--just the autopsy prep! Could explain the diarhea in that girl, huh? Wonder if she was last in line?

I would have no hesitation recommending it to those of you who are flying and need protection and/or will come off the warfarin after a few months. I have exchanged emails with other women who have dissolved PE and major DVT's w/ this stuff. Course, our bodies do some of the lysing you know, but the beauty of NK is that it promotes your body's natural ability to dissolve the clot--that is what encouraged me about it.

In one test, they induced clot in dogs hearts (aaahhhh, I know it's terrible) and the dogs that received the natto had dissolved their clot in 5 hours! (If I remember this right.) In another test they drop the natto substance into a pretri dish of thrombus and can watch it dissolve! These are the most exciting things I remember from my reading.

Richard--Yes, my insurance is covering my tests. They also know that I am taking natto and have no problem w/ it--tho I have not tried to get reimbursement for the NK yet--maybe I should. They do periodically ask me about the progress. I have a personal nurse advocate with my insurance company. They consider me a 'special case' (my friends would concur for reasons other than health) and they really have approved almost anything I need. I cannot complain, and am very grateful. I was initially concerned that NK might drop my blood pressure too low since it is very low to start w/. I asked if they would cover an overnight hosptial stay if my doc wanted to start me on it under supervision or something and they said as long as he felt it was medically necessary, they would. I didn't do that after all, but they have been great! I've only had $2,500 out of pocket on a $950,000 tab so far! I almost feel guilty w/ many of the medical system frustrations so many of you have. I will follow w/ more later. --sb
3765
Re: Nattokinase
Reply #17 by Marie
Posted: January 23, 2008 at 09:56
Donna,
Who do you see privatly, after coming off warfarin. I have a private health plan & am finding it extremely difficult to see anyone. I go to the GP & explain my symtems one has told me that the clot will break down over time & the other has told me the clot will not go but my other veins will get bigger to compensate. He has sent me to see a Gastro Entrologist - because I over the last couple of weeks have felt unwell out of breath after short walks (feels like I have been on a 5 mile hike)& I can feel the blood pumping around my body especially in my head. If I could go in and ask the doctor which specialist I hould be seeing that would be great. (The doctor & haematologist has told me that no one particularly deals with the clot)
3766
Re: Nattokinase
Reply #18 by Donna
Posted: January 23, 2008 at 19:06
Hi Marie,I went to see a vascular surgeon. I phoned the company I have my health plan with and they told me to make the appointment.He was great and was able to explain more to me than all the doctors I had seen in hospital.My leg is still very swollen and he told me that might never go down due to the damage caused by the dvt
3773
Re: Nattokinase
Reply #19 by Claudine (Australia)
Posted: January 24, 2008 at 01:46
From reading the responses it appears that there is a strong recommendation to go on Nattokinase after warfarin therapy.
I was wondering whether anyone has gone to a herbalist/nutritionist/naturopath/chinese doc to get more information on nattakinase or whether either of these specialists have recommended it.

PS this chat area could be addictive. Is anyone addicted?
3778
   1 2 3 4 5 6 7 8 [Next Page>>]
Reply to this topic    or     Start New Topic

Your Name:
Reply Subject: Re: Nattokinase
Comments:
(You may enter up to 3001 characters)

characters left

Type the characters shown in the image for verification 2: