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Does exercise increase inr?
Started by Kerri
Posted: March 3, 2011 at 06:11
I have finally started exercising again but now my inr has shot up from 1.9 to
3.7. Could this be from the exercise?? Nothing else has changed??? Thanks :)
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Re: Does exercise increase inr?
Reply #1 by Tim in Minnesota
Posted: March 3, 2011 at 21:18
Hi Kerri:

It is possible that exercise would affect your INR levels. I think it is due to speeding up the metabolism. However, everyone seems to be different as far as I know. Some may have no affect. When I went from just walking to more vigorous exercise my INR actually dropped. The INR nurse said it could be do to increased level of exercise that may speed up the metabolism which then speeds up how quickly the warfarin is processed. She wasn't sure, but it made sense to me.

I would caution though that to go from 1.9 to 3.7 seems to be an awfully dramatic change. Maybe there is something else going on?

Tim
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Re: Does exercise increase inr?
Reply #2 by Kerri
Posted: March 3, 2011 at 21:58
Thanks Tim. That actually does make sense! So why my inr has gone up....hmmm good question.
I have been off warfarin for 7 days and my inr was 3.4, so not really much of a change there.
Not sure of what else it could be. Is all very confusing this dvt thing!! I'm thinking I might go see a specialist because my gp is quite whelming sometimes with her advice.
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Re: Does exercise increase inr?
Reply #3 by Tim in Minnesota
Posted: March 4, 2011 at 15:53
Kerri:

You'll probably notice on this site that many people see either a hemotologist or a Vascular Doctor in addition to their GP. I think the hemotologist is primarily in case of a blood disorder. Vascular doctors are used to dealing with DVT's and the surrounding issues.

You will also find that there are many people on this site that have dealt with vascilating INR levels, and sometimes it is hard to know why. Warfarin is processed in the liver, and the liver provides many services to your body. Also, the function of your liver is affected by many biological factors. I have been fortunate in that my INR has been pretty stable over the past 1.5 years. Some are not as fortunate. The best thing you can do to help yourself is to keep as many things as possible constant including alchohol intake, diet, exercise, medication, etc.
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Re: Does exercise increase inr?
Reply #4 by Kerri
Posted: March 8, 2011 at 11:02
Thanks Tim. I am in australia and they think we don't want to spend the money
on specialists. Funny thing is, I am a vet tech and we always offer the best ie
referrals to specialists. I just dont have faith anymore in my doctor as she has
not been consistent hence why my questioning of a specialist: thankyou for your
replies :) I do appreciate it :)
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Re: Does exercise increase inr?
Reply #5 by cm
Posted: March 9, 2011 at 07:48
I always assumed that inr was lowered by increased activity. Or at least thats the
only thing I can think of changing my INR. I started working out twice a day and cut
out nearly all vitamin k and my inr lowered from 2.2 to 1.5. So for the past 6 weeks I
have had my coumadin adjusted. I just assumed that faster metabolization meant that
coumadin leaves the blood faster. I guess there could be a zillion reasons for your inr
drop... I would do like Tim in Minnesota says "keep as many things as possible
constant".
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Re: Does exercise increase inr?
Reply #6 by Tim in Minnesota
Posted: March 10, 2011 at 14:12
I think that cm's comments are very insightful as to the processing of warfarin in your system...that increased in motabalism increases how quickyl warfarin in processed in your liver, thereby reducing the store or build up of warfarin and decreasing the INR levels. Therefore, increased levels of activity which would increase the metabolism would reduce INR levels requiring increased dosages of warfarin.

Exercising 2x/day? I have enough trouble getting in 1 workout/day! :)
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Re: Does exercise increase inr?
Reply #7 by Kerri
Posted: March 10, 2011 at 19:50
I do agree with all of the above, but still wondering why my inr shot up?
Everything is the same except I started exercising again. Maybe I am just
backwards in life :)
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Re: Does exercise increase inr?
Reply #8 by Luisa
Posted: November 14, 2012 at 21:02
I am in the process of figuring that out. I have been on Warfarin for
about 4 yrs, since 2008, (had a blood clot in my lung). I was sedentary
most of the time, until recently. I have been working out 1hr a day 5x a
wk. My INR was ususally around 2.1 - 2.5. I had it checked yesterday and
my INR is 5.3 ! My primary looking into it, will post with more info
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Re: Does exercise increase inr?
Reply #9 by Finding our if exercise increases inr
Posted: November 15, 2012 at 22:03
I am in the process of figuring that out . I have been on Warfarin for
about 4 yrs, since 2008, ( had a blood clot in my lung ). I was
sedentary most of the time, until recently, about a month. I have been
working out 1 hr a day 5x a wk. My INR was usually around 2.1-2.5. I had
it checked yesterday and my INR is 5.3! My Primary Dr is looking into
it, will post when I have more info....
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Re: Does exercise increase inr?
Reply #10 by Kage
Posted: November 16, 2012 at 06:23
Hi!
I have only been told not to do too much exercise in case I fall or
something and end up with internal bleeding.
I am one of those people who exercise a lot for a couple of months and
then do nothing for a few months and it has never affected my INR.
Hope you can find a balance because as we all know, exercise is vital to
a healthy body too.
take care
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Re: Does exercise increase inr?
Reply #11 by Mitzi
Posted: July 24, 2013 at 13:49
After a heart attack in 2012 I was told to keep exercising, but to walk, not run until given permission. I ran half-marathons. My INR should be between 2 and 3 and it generally stays not too bad, but then it shoots up for a day and goes back down later. Today it went to 3.2. I don't know why. My exercise level stays the same and my eating habits stay pretty constant, so it's a mystery to me. I would have thought that more exercise would cause the INR to drop, as it seems to for many people, but mine doesn't. It is checked three times a week, and my little graph looks O.K. except for the sudden spikes about twice a month. I wish I knew why I get the spikes.
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Re: Does exercise increase inr?
Reply #12 by Chris (51)
Posted: August 20, 2013 at 13:58
My experience is that inactivity lowers my INR, exercise raises it. It
also appears to be linked to my blood sugar levels, increased blood
sugar lowers my INR, healthy levels appear to raise it. I went from 2.4
to 5.9, and the only major change has been a 5 mile daily cycling
commute.

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